Tim Benke, PhD, MD

Tim Benke is Ponzio Family Chair in Neurology Research and Professor of Pediatrics, Pharmacology, Neurology and Otolaryngology at University of Colorado School of Medicine. He joined the University of Colorado, School of Medicine and Children’s Hospital Colorado (CHCO) in 2002 where he is Research Director of the Neuroscience Institute. He initiated the multi-disciplinary Rett/CDKL5/FOXG1 Clinic in 2011 at CHCO (recognized as a Center of Excellence), where he is the Medical Director. Dr. Benke was site PI for the NIH funded Natural History Study (NICHD U54 HD061222 Percy, PI) and collaborates in clinical trials and outcome measure development in RTT (NINDS R61NS130216, Marsh/Neul, PD; DOD PR221983, Neul, PI; Acadia NCT04181723; Neurogene, NCT05898620), MECP2 Duplication Syndrome (IONIS, NCT06430385) and CDKL5 (NINDS- U01NS114312, Benke, PD; Loulou Foundation NCT05373719; Marinus NCT03572933). He is leading the male RTT project funded by IRSF and RMRA (NCT06346106). He oversees the collaborative GRIN variant registry (Emory/Traynelis/Simons). His translational lab collaboratively studies the molecular impact of GRIN variants (Emory/Traynelis/Simons), the impact of earl-life seizures (NINDS R21 NS101288) and CDKL5 (NINDS R21 NS112770, IFCR) on synaptic physiology and plasticity.