We are currently evaluating institution-based, collaborative, multidisciplinary clinical research teams to join the IMPACT Network. The Request for Application (RFA) is now closed, awards will be announced in mid-2026.
IMPACT Network
The Innovative Medicine and Precision Approaches to Clinical Trials (IMPACT) Network, the first Frontier Clinical Hub, is a robust and collaborative international network of sites designed to accelerate clinical trial readiness and clinical trial implementation for syndromic and non-syndromic forms of autism.
Our Objectives
- Enable standardized and coordinated quantitative phenotyping and biomarker discovery across participating sites
- Deliver cutting-edge clinical research interventions
- Contribute to foundational, collaborative human neuroscience research
- Enable sufficiently powered clinical trials
Integration
The ARIA initiative promotes a connected environment in which all ARIA components—Research Hubs, Community Collaborators, Open Science, and Centralized Services—interact to propel scientific discovery.
Research Hubs
Promising discoveries and therapies from the Frontier Science Hubs will be tested within the IMPACT Network’s core sites.
Community Collaborators
Community Collaborators provide their perspectives to support the IMPACT Network and Frontier Science Hubs.
Centralized Services
Centralized Services includes the Clinical Coordinating Center and the Data Coordinating Center.
The Clinical Coordinating Center serves as the nucleus of the IMPACT Network and provides clinical research operations and administrative leadership and oversight.
The Data Coordinating Center will manage all data collected at IMPACT Network sites, ensuring that data collection is standardized and integrated from multiple sites.
